Sao Paulo will host Nacional at Estadio de Morumbi in the second leg of their Copa Libertadores round of 16 tie, with both teams vying for a place in the quarter-finals. The first leg in Montevideo ended in a 0-0 draw, marking only the second time in this tournament that neither side managed to score.

Sao Paulo struggled offensively in the first leg, failing to register a shot on target despite dominating possession. However, they have been solid defensively, keeping three consecutive clean sheets in the Libertadores. At home, they were unbeaten in the group stage, without conceding a single goal. Despite a recent dip in form with a domestic loss to Palmeiras, Sao Paulo has a strong record in knockout matches, especially when scoring first.

Nacional, on the other hand, showed defensive resilience in the first leg, securing only their second clean sheet in this year's tournament. Historically, they have struggled against Brazilian teams in the knockout stages and have not won in regular time in their last three matches across all competitions. However, they have a history of putting up a fight, as seen in last year's round of 16, where they took Boca Juniors to penalties after a 2-2 draw in the second leg.

In terms of team news, Sao Paulo will be without Pablo Maia due to a thigh issue, along with other key players like Alisson, Erick, and Patryck due to various injuries. Nacional will miss Christian Ebere, Gonzalo Carneiro, and Renzo Sanchez, who are recovering from long-term injuries. Both teams will rely heavily on their defensive solidity, with Sao Paulo hoping to capitalize on their home advantage and experience in crucial fixtures.

Given Sao Paulo's strong defensive record at home and their ability to perform in high-pressure situations, they are likely to edge out Nacional with a narrow victory, securing their place in the quarter-finals.

在解放者杯16强第二回合比赛中，圣保罗将在莫伦比体育场主场迎战国家，两支球队都将争夺1 / 4决赛的席位。在蒙得维的亚的首回合比赛以0-0平局结束，这是本届杯赛中第二次双方都没有进球。

圣保罗队在第一回合的进攻中表现不佳，尽管控制了控球权，但却没有一次射门。然而，他们的防守很稳固，在解放者的比赛中连续三场不失球。在主场，他们在小组赛中保持不败，一球未失。尽管最近在国内比赛中输给帕尔梅拉斯(Palmeiras)，状态有所下滑，但圣保罗在淘汰赛中有着出色的战绩，尤其是在率先进球的情况下。

另一方面，国家队在首回合比赛中表现出了很强的防守韧性，这是他们今年第二次零封对手。从历史上看，他们在淘汰赛阶段对阵巴西队时表现不佳，而且在所有赛事的最后三场比赛中都没有在常规时间获胜。然而，他们有一段奋起抗争的历史，就像去年的16强一样，在第二回合2-2战平博卡青年队后，他们将博卡青年队罚进了点球。

球队方面的消息是，由于大腿受伤，圣保罗将失去巴勃罗·马亚，其他关键球员如阿利森、埃里克和帕特里克也将因各种伤病缺阵。国家队将错过埃贝雷、卡内罗和桑切斯，他们正在从长期伤病中恢复。两支球队都将在很大程度上依赖于他们的防守稳固，圣保罗希望利用他们的主场优势和在关键赛程的经验。

鉴于圣保罗在主场的强大防守记录以及他们在高压环境下的表现能力，他们很可能以微弱的胜利险胜国民队，确保他们进入四分之一决赛。