Bayer Leverkusen has been in spectacular form under coach Xabi Alonso, winning 11 of their 12 Bundesliga games in an unbeaten start to the season, placing them at the top of the league. They aim to secure a record seventh consecutive home triumph. Midfielder Jonas Hofmann highlighted their clinical and focused approach after the recent 3-0 win against Werder Bremen. Leverkusen expects Florian Wirtz to be available against Borussia Dortmund, while striker Victor Boniface seeks to end a four-game scoreless streak. Borussia Dortmund, led by Edin Terzić, secured an impressive 3-1 victory against AC Milan in the UEFA Champions League, marking their third straight win in the competition. The team is in confident mood, having also achieved a 4-2 comeback victory against Borussia Mönchengladbach in the Bundesliga. Despite some players being doubtful due to colds, Dortmund can count on the attacking prowess of Jamie Bynoe-Gittens, who has registered two goals and an assist in his last two games in all competitions.Jeremie Frimpong and Alejandro Grimaldo, Leverkusen's defenders, are the most prolific defensive pair across Europe's top five leagues this season with 11 goals and nine assists between them.Leverkusen has won their first six home games of the campaign, and achieving seven would be a club record. The prediction leans towards a home win for Bayer Leverkusen considering their outstanding form and home record.

勒沃库森在阿隆索的带领下表现出色，在本赛季的12场德甲比赛中取得11场胜利，保持不败，排名联赛第一。他们的目标是取得创纪录的主场七连胜。在最近3-0战胜云达不莱梅后，中场乔纳斯·霍夫曼强调了他们的冷静和专注。勒沃库森希望维尔茨能在对阵多特蒙德的比赛中上场，而前锋博尼法斯则希望结束四场零进球的纪录。在特尔齐奇的带领下，多特蒙德在欧冠联赛中以3:1大胜AC米兰，这也是多特蒙德在欧冠联赛中的三连胜。球队信心十足，在德甲联赛中以4-2逆转战胜了俄罗斯Mönchengladbach。尽管一些球员因感冒而无法上场，但多特蒙德可以依靠杰米·拜诺-吉滕斯的进攻能力，他在最近两场比赛中取得了两个进球和一个助攻。勒沃库森的后卫Jeremie Frimpong和Alejandro Grimaldo是本赛季欧洲五大联赛中最多产的防守组合，他们共有11个进球和9次助攻。勒沃库森在本赛季的前6场主场比赛中取得了胜利，如果能取得7场胜利，那将是俱乐部的纪录。考虑到勒沃库森出色的状态和主场战绩，预测倾向于主场获胜。